), Berlin, Germany ; Carmen Schade-Brittinger - Coordinating Centre for Clinical Trials Marburg (KKS Marburg), Philipps University Marburg, Germany ; Frank Wissing - German Association of Medical Faculties (MFT), Berlin, Germany ; Thorsten Ruppert - German Association of Research-Based Pharmaceutical Companies … Author Affiliations: Orthopedic Department, University Of Regensburg, Bad Abbach, Germany (Dr Haake); Institutes For Medical Biometry And Epidemiology (Drs MüLler And SchäFer) And Medical Psychology (Dr Basler) And Centre For Clinical Trials (Ms Schade-Brittinger), Philipps-University Marburg, Marburg, Germany; Departments Of Pain Management, Bg-Kliniken Bergmannsheil (Dr … 1, 2 The mainstay of treatment of advanced ovarian cancer is primary surgery aiming at complete resection followed by platinum and paclitaxel chemotherapy. Peritoneal carcinomatosis has been reported to be either a negative predictor for resectability or a negative prognostic factor, or both. dezwaan.martina@mh-hannover.de. Epithelial ovarian cancer is the fifth most frequent cause of cancer death in women and remains the leading cause of gynecologic cancer-related deaths in the US and Europe. Elisabeth Maurer 1 , Alexander Reuss, Katja Maschuw, Behnaz Aminossadati, Thomas Neubert, Carmen Schade-Brittinger, Detlef K Bartsch Affiliation 1 Department of Visceral, Thoracic and Vascular Surgery Universität Gießen und Marburg GmbH, Marburg; Clinica Trials Coordination Center (KKS), Philipps-Universität Marburg, Marburg. transcutaneous skin stapling for closure of midline or horizontal skin incision in elective abdominal surgery and their outcome on superficial surgical site infections – INTRANS: study Philipps-Universität Marburg Koordinierungszentrum für Klinische Studien (KKS) Ms. Carmen Schade-Brittinger. Germany: Co-ordinating Centre for Clinical Studies (KKS), Philipps University, Marburg (B Lenz, J Rochon, C Schade-Brittinger, M Wittenberg, H Wolf). The authors thank S. Eichner, A. Krüger, M. Schulze (AGO-OVAR study office Kiel, Germany), and C. Ackermann, G. Elser (AGO-OVAR central unit Wiesbaden, Germany) for data management and technical support, and J. Rochon and C. Schade-Brittinger (KKS Marburg, Germany) for statistical support. Anja Rinke, Hans-Helge Mu¨ller, Carmen Schade-Brittinger, Klaus-Jochen Klose, Peter Barth, Matthias Wied, Christina Mayer, Behnaz Aminossadati, Ulrich-Frank Pape, Michael Bla¨ker, Jan Harder, Christian Arnold, Thomas Gress, and Rudolf Arnold From the Department of Internal Medi-cine, Division of Gastroenterology and Marburg (KKS), Germany for data entry and data management including. Independent Trials (KKS), Marburg, Germany effective than a specific psychotherapy. Karl-von-Frisch Str. Almost all retrospective trials pointed out that a benefit of surgery for recurrent ovarian cancer may be limited to patients in whom a macroscopic complete resection could be achieved. Management of clinical trials working group Ensuring the quality of science-driven trials. 3rd International Ovarian Cancer Consensus Conference: outstanding issues for future consideration. The authors thank the 156 patients, their families, the investigators and study teams at the participating sites, the Independent Data Monitoring Committee (M Bookman [Chair], K Winter and D Fink), the statisticians (J Rau, C Schade-Brittinger, B Aminossadati [KKS], L Mitchell, U Freudensprung, N Martin [former Roche employees], A Cardona [Roche] and J Oyee [Covance]), Y Ghazi (Roche) … A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Stuart G, Avall-Lundqvist E, du Bois A, et al. The EARLYSTIM Study compared deep brain stimulation (DBS) with best medical treatment (BMT) over 2-years, showing a between-group difference of 8.0 from baseline in favor of DBS in health-related quality of life (HRQoL), measured with the PDQ-39 SI (summary index). Alexander Reuss, Karin Weide & Carmen Schade-Brittinger. Trials (KKS), Marburg, Germany (C Schade-Brittinger MA) Correspondence to: Prof Stephan Zipfel, Department of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Tübingen, Germany stephan.zipfel@ med.uni-tuebingen.de clinical … The Center for Clinical Trials (KKS Marburg) is an independent facility of the Medical Faculty of the Philipps-University Marburg. We thank Dr. Gabriele Kohlböck for conducting the … INTERBED: internet-based guided self-help for overweight and obese patients with full or subsyndromal binge eating disorder. carmen.brittinger@kks.uni-marburg.de Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number): Rinke A, Müller HH, Schade-Brittinger C, Klose KJ, Barth P, Wied M, Mayer C, Aminossadati B, Pape UF, Bläker M, Harder J, … Metabolic syndrome (MS) is an aggregation of central obesity and metabolic abnormalities that confer an increased risk of cardiovascular disease (CVD) and type 2 diabetes (T2DM) .Approximately 25% of the US general population has MS .The clinical utility of MS for predicting cardiovascular risk beyond individual risk factors is subject to intense international discussion . 2009). 35043 Marburg. 1 Epilepsy Center Hessen, Dept. Department of Psychosomatic Medicine and Psychotherapy, Hannover Medical School, Hannover, Germany. The authors compared these drugs with regard to their efficacy and tolerability in the initial monotherapy for epilepsy. Background Of the newer antiepileptic drugs, lamotrigine (LTG) and levetiracetam (LEV) are popular first choice drugs for epilepsy. Du Bois, U. Wagner This document is property of the AGO Study group and the Philipps - University of Marburg. Das KKS Marburg wurde im April 2000 als eine eigenständige Einrichtung der Medizinischen Fakultät der Philipps-Universität Marburg gegründet.. Am 01.01.2019 wurde zusätzlich eine Außenstelle an … Introduction. Introduction Success rates of psychotherapy in post-traumatic stress disorder related to childhood maltreatment (PTSD-CM) are limited. Biometrical supervision is conducted by the Institute of Medical Biometry and Epidemiology, Marburg (Prof. Schäfer). Authors: P. Harter, A. Reuß, C. Schade-Brittinger, A. Carmen Schade-brittinger. KKS Marburg Date Carmen Schade-Brittinger Coordinating Investigator Date Prof. Dr. Jürgen Behr Deputy Coordinating Investigator Date Prof. Dr. Andreas Günther Statistician Date Petra Neuser . Koordinierungszentrum für Klinische Studien Marburg. : 202/12, Ethik-Kommission des Fachbereichs Medizin der Philipps-Universität Marburg end of 1:1-Block organizational data start of 1:n-Block secondary IDs https://www.frontiersin.org/articles/10.3389/fneur.2015.00177 No particular research ethics committees at every participating centre (C Schade-Brittinger MA) treatment, however, was consistently superior to any approved the study. Alexander Reuss 1 , Andreas du Bois 2 , Philipp Harter 2 , Christina Fotopoulou 3 4 , Jalid Sehouli 4 , Giovanni Aletti 5 , Frederic Guyon 6 , Stefano Greggi 7 , Berit Jul Mosgaard 8 , Alexander Reinthaller 9 , Felix Hilpert 10 , Carmen Schade-Brittinger 11 , Dennis S Chi 12 , Sven Mahner 13 V01F Study Protocol: RELIEF EudraCT 2014-000861-32 3 of 67 13.07.2015 of Neurology, University Hospitals Giessen & Marburg and Philipps-University Marburg, Marburg, Germany 2 Coordinating Center for Clinical Trials (KKS), Philipps-University Marburg, Germany 3 Department of Neurology, University of Ulm, Ulm, Germany and Department of Neurology and 4030 Background: Octreotide LAR (O) compared to placebo (P) lengthens significantly time to tumor progression (TTP) in patients with metastatic midgut neuroendocrine tumors (Rinke et al. Data management is provided by the Coordination Center for Clinical Trials (KKS), Marburg (C. Schade-Brittinger). Telephone: 06421-2866509. Placebo-controlled, double-blind, prospective, randomized study on the effect of octreotide LAR in the control of tumour growth in patients with metastatic neuroendocrine midgut tumours: a report from the PROMID Study Group. The information data of the enrolled patient is transferred to the KKS by fax. Ursula Ghulami, KKS Marburg sponsor representative, Philipps University Marburg Medical Center: ClinicalTrials.gov Identifier: NCT00712218 Other Study ID Numbers: AGO-OVAR OP.3 : First Posted: July 9, 2008 Key Record Dates: Last Update Posted: March 4, 2020 Last Verified: March 2020 Schade-Brittinger C. Einbindung eines KKS in ein Comprehensive Cancer Center; Philipps-Universität Marburg, Symposium 2005. Ovarian cancer is the leading cause of death from gynecological malignancies and is in most cases diagnosed at an advanced stage. Henning Schauenburg. The antiproliferative response was more pronounced in patients with low (≤ 10%) hepatic tumor load (HL). accelerates the progression of chronic congestive heart failure (CHF), and studies in patients with CHF and left bundle branch block (LBBB) have demonstrated its negative prognostic impact on survival.4Cardiac Martina de Zwaan. Coordinating Centre for Clinical Trials Marburg (KKS Marburg), Philipps-University Marburg, Marburg, Germany. 18 May 2018 - Annual Materials Researchers Day in Marburg; 24 May 2018 - DFG Supports "Chromatin Changes in Differentiation and Malignancies" and "Innate Immunity of the Lung: Mechanisms of Pathogen Attack and Host Defence in Pneumonia" for Continuing Four Years; 28 June 2018 - 9 Million Euro LOEWE-Funding for Research Campus of Central Hessen 4. Ansprechpartner: Carmen Schade-Brittinger (carmen.brittinger@kks.uni-marburg.de) Seitens der Deutschen Forschungsgemeinschaft (DFG) und des Bundesministeriums für Bildung und Forschung (BMBF) gibt es unterschiedliche Programme zur finanziellen Förderung klinischer Studien für wissenschafts-initiierte Projekte. University of Giessen and Marburg Lung Center (UGMLC), University Hospital Giessen, Justus Liebig University of Giessen, Giessen, Germany. KKS has more than 17 years of experience in the planning, organization and conduct of multicenter clinical trials and an excellent expertise in clinical trials methodology, data science, Good Clinical Practice, multicenter data management and quality assurance. Correspondence to: other approach. start of 1:1-Block address primary-sponsor. Konstantin Mayer Trauma-focused psychodynamic therapy and STAIR Narrative Therapy of post-traumatic stress disorder related to childhood maltreatment: trial protocol of a multicentre randomised controlled trial assessing psychological, neurobiological and health economic outcomes (ENHANCE) Authors Insa Bruns - Coordination Center for Clinical Studies (KKS-Netzwerk e.V. A multicenter randomized controlled trial. Eligibility assessment, obtaining informed consent, and enrolling the patient in the trial is done by the respective study centres. end of 1:1-Block address primary-sponsor. start of 1:1-Block address contact primary-sponsor. Clinica Trials Coordination Center (KKS), Philipps-Universität Marburg, Marburg; Alexander Reuss, Behnaz Aminossadati, Carmen Schade-Brittinger Figure Flow of … Despite optimal therapy consisting of surgery and platinum/taxane-based chemotherapy about half of the patients will die within 5 years after the first diagnosis.1 In 1934, Meigs was the first to perform cytoreductive surgery in advanced ovarian … 2005;16(S8):viii36-viii38. ... (KKS) in Marburg, Germany. 4 Coordinating Centre for Clinical Trials, Philipps-Universität Marburg, Marburg, Germany Carmen Schade-Brittinger Coordinating Center for Clinical Trials - KKS, Philipps-Universitat Marburg, Marburg, Germany Harald Gündel Department of Psychosomatic Medicine and Psychotherapy, University Ulm Medical Center, Ulm, Germany Kerstin Weidner Rinke A, Müller HH, Schade-Brittinger C, Klose KJ, Barth P, Wied M, Mayer C, Aminossadati B, Pape UF, Bläker M, Harder J, Arnold C, Gress T, Arnold R; PROMID Study Group. This study obtained complementary information about the importance of the change in HRQoL as measured by the PDQ … Germany. The KKS Marburg is an independent facility of the Medical Faculty of the Philipps University of Marburg, which supports clinical trials on oncology, internal medicine, cardiology, surgery, neurology and orthopedics. German Centre for Infection Research (DZIF); the Justus Liebig University, Philipps-Universitaet Marburg, Technische Hochschule Mittelhessen University of Applied Sciences and the Paul-Ehrlich-Institut Langen form the DZIF-site Gießen-Marburg-Langen; speaker Trinad Chakraborty (JLU), deputy speaker Stephan Becker (UMR); in cooperation with the Campus Research Focus “Lung and Heart … We also thank Kathleen Pike for her support and for making the treatment manual used by her group available. (leading) Ethics Committee No. The KKS Marburg (Dr. Carmen Schade-Brittinger) contributed the external randomization procedure. Annals of Oncology. INTRODUCTION.